1. Increased levles of ATP in the cell close or open ATP dependent K+ channels?
ID: 178822 • Letter: 1
Question
1. Increased levles of ATP in the cell close or open ATP dependent K+ channels?
2. Beta cells like all other cells have high or low levels of K+ inside?
3. Improperly folded insulin molecules that are result of mistakes in translation are destroyed in ___________, the large complexes of proteases localized in the cytosol. To be recognized and "allowed entry" to the ________ "doomed" proteins undergo ___________ a process of attachement of a small cytosolic protein.
4. Insulin has more physiological effects than just glucose transport. In a "big picture" the physiological roles of insulin are _____________, _____________, ____________.
5. The presence of glucose in urine is the result of the ________ (property of transporter protein) of the transporter protein that is responsible for glucose reabsorption in the kidneys. This transporter protein ________ has the saturation threshold of about 180 mg/ml.
Explanation / Answer
1. Increased levles of ATP in the cell close ATP dependent K+ channels.
2 . Beta cells like all other cells have low levels of K+ inside.
3a. Improperly folded insulin molecules that are result of mistakes in translation are destroyed in Endoplasmic reticulum , the large complexes of proteases localized in the cytosol.
3b .To be recognized and "allowed entry" to the Golgi complex "doomed" proteins undergo Glycosylation a process of attachement of a small cytosolic protein.
4. Physiological roles of insulin are Control the glucose uptake into muscle and adipose tissue, increase DNA replication, Increase Glycogen synthesis, Increased potassium uptake, decreased gluconeogensis, increase lipid synthesis, increased esterification, decreased lipolysis, decreased proteolysis, decreased autophagy, increased aminoacid uptake, increased HCL production, decreased renal sodium excretion, aterial muscle tone.
5.The presence of glucose in urine is the result of the Renal glycosuria/Diabetes property of transporter protein
This transporter protein Sodium Glucose co transporter has the saturation threshold of about 180 mg/ml.
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