Research Study 3 The pedigree below is for a family that has several afmlictions

Question

Research Study 3 The pedigree below is for a family that has several afmlictions that are believed to have the same genetic cause. Six regions on the X chromosome were examined (the six regions are named MAOA," "MAOB," "DXS8054, "DXS1039," "DXS991," and "DXS1275") to attempt to identify a Figure 1. specific gene or region of the gene that was causing these disorders. The pedigree Alleles or genotypes for MAOA, -5 2 MAOB, MAOA 2 DXS8054 2DXS1039, DXS991 DXS1275 3 DXS991, and DXS1275 are u shown for 0 22 3 4 the MAOA 1 individuals in X58054 XS1039 i this extended Macro- s encephaly DXS991 DXS1275 family. MACA 2 refers to head DXS1039 2 DXS991 2 DXS1275 circumference at or above the 90th e. Learning Epilepsy The pedigree utilizes shading to show which ailment or combination of ailments the individual has (see key at bottom of figure). To the left side of the pedigree, the six regions are listed; to the right, the alleles or genotype of the individual is noted. For instance, individual II-1 has an MAOA genotype of (2/3), a MAOB genotype of (3/1), and a DXS1275 genotype of (3/5). The dot in the middle of the circle indicates that she is not afflicted by the ailment, but shares suspect genetic information with those that are aflicted. Individual II-5 only has allelic information since

Explanation / Answer

A. The pedegree is showing X linked dominant pedegree. Here the dominant allele MAOB is carried on X chromosome.

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