In the biosynthesis of complex lipids, components are assembled by transfer of t

ID: 190500 • Letter: I

Question

In the biosynthesis of complex lipids, components are assembled by transfer of the appropriate group from an activated donor. For example, the activated donor of acetyl groups is acetyl-CoA. For each of the following components of a complex lipid, identify the activated form by moving the activating group into the box next to the component. glucosy UDP OOC-CH2CO-CoA alactosyATP oshate -norganic phosphate) meth CoA ADP ethanolamine isopenteny fatty acy hsadenosyl AMP hamacysteine CoAhoaderssne AMP ADPohosyoate GDP phosphate ooC ATP CDP DP

Explanation / Answer

Glucosyl

UDP

The glucosyl donor is a type of mono or oligosaccharide which bind to the glucosyl acceptor and forms the glycosidic bond. The UDP acts as donor group for glucosyl

Galactosyl

ATP

The ATP is a donor group for galactosyl and on binding, the molecule is activated.

Methyl

CoA

The co-enzyme A (CoA) acts as active donor group for the methyl. The methyl-CoA is an activated form which helps in formation of many other products.

3-isopetenyl

AMP

It is formed in presence of enzyme isopentyl transferase which is a key intermediate in formation of many other products.

CH2CO-CoA

OOC

It is the donor and as it bind to the acceptor group of the molecule, it is activated which acts as intermediate molecule.

Inorganic phosphate

Pyrophosphate

The pyrophosphate is a active group and it binds to the inorganic phosphate for creating an active molecule.

Ethanolamine

CDP

The activated donor for ethanolamine is CDP, and it can be used for later transferring the group to form other molecule.

S-adenosyl Homocysteine

Fatty acyl

It is a substance which leads to activation of the fatty acids. It binds to the same and activates the molecule by binding to the acceptor group.