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A 24-year-old man complains of increased appetite, although his body weight is b

ID: 192292 • Letter: A

Question

A 24-year-old man complains of increased appetite, although his body weight is below normal. Laboratory investigations reveal that he is excreting 20 grams of glucose per day in his urine, while having a normal GFR (180 L/day) and plasma glucose (1 gr/L). Fanconi's syndrome is suspected. Which of the following is the most likely reason for glucose excretion in his urine?

Increased filtered load of glucose. Laboratory tests are not reliable. Decreased Tm for glucose. Increased secretion of glucose.

Explanation / Answer

Decrease Tm (absorption ) for glucose  is one of the reason in Faconi's syndrome where patient's ability to secrete or break certain compounds increased .

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