Jump to... hniques, ndrei Dyban and VS. Baranov created mice that were trisomic

Question

Jump to... hniques, ndrei Dyban and VS. Baranov created mice that were trisomic for each of the different mouse chromosomes (Cytogenetics of Mammalian Embryonic Development. Oxford: Oxford University Press,Clarendon Press; New York: Oxford University Press, 1987). 2.5 They found that only mice with trisomy 19 developed fully Mice trisomic for all other chromosomes died during development 2.0 Chr 1 r 6 For some of these trisomics, they compared the length of development, before the embryo died, as a function of the size of the chromosome that was This data is presented in the graph on the left (E. Torres, B. R. Williams, and A. Amon. 2008. Genetics 179:737-746 Fig. 2B.). Chr 13 Chr 14 Chr 10 1.0 Chr 12 t in three copies Chr 16 Chr 18 0.5 0.0 11 12 13 14 15 16 17 18 Choose the statements that best describe the findings based on the graph presented Length of embryanic development idays) Mice trisomic at small chromosomes survived longer than mice trisomic at larger chromosomes. There is an inverse relationship between size of the trisomic chromosome and the length of embryonic development There is a positive correlation between size of the trisomic chromosome and the length of embryonic development The longer the mice developed, the larger their chromosomes became. Continued below Group &ylew; Solution Check Answer 0 Next Exit Previous Hint

Explanation / Answer

From the graph it can be clearly seen that there is a inverse realtonship between the length of chromosome and the survival of the mouse .The most probable answer to these may be (d) as a larger chromosome will have a large number of genes and therefore a more number of genes will be affected in the trisomy and thus causing early death

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