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Cells are able to modulate between NADPH and ribose-5-phosphate production by al

ID: 200665 • Letter: C

Question

Cells are able to modulate between NADPH and ribose-5-phosphate production by altering pathways. The cycle below would be used if 2 NADP 2 NADPH Glucose 6-phosphate 5-phosphate co, Fructose 5-phosphate Ribose 6-phosphate Fructose 1,6-bisphosphate Dihydroxyaceto3-phosphate xyacetone-Glyceraldehyde ribose-5-phosphate is needed and NADHP is not if NADPH levels are too high D if ribose-5-phosphate levels are too low NADPH & ribose-5-phosphate are both needed NADPH is needed and ribose-s-phasphate is not needed 11

Explanation / Answer

when both the NADPH and Ribose-5-phosphate both are needed.

Depending on the body's state, ribulose 5-phosphate can reversibly isomerize to ribose 5-phosphate. Ribulose 5-phosphate can alternatively undergo a series of isomerizations and transaldolations and transketolations that result in the production of other pentose phosphates and fructose 6-phosphate and glyceraldehyde 3-phosphate (both intermediates in glycolysis).

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