A 60-year-old woman with anemia is admitted to the hospital. Her hematocrit is 1

Question

A 60-year-old woman with anemia is admitted to the hospital. Her hematocrit is 17% and she has been experiencing subtle gastrointestinal bleeding over many weeks. Her physician requests 4 units of red blood cells for transfusion. The patient’s RBCs phenotyped as group AB, D-positive. Her antibody screen is negative on the sample drawn in the emergency room, but her records indicate a previously detected anti-E. Only three group AB, D-positive red blood cell units are available in the blood bank’s inventory. The blood bank’s inventory contains RBC donor units of all ABO and D types.

Additional Testing: After antigen screening the 4 units of red blood cells for the E antigen, one of the group AB D-positive units is E-positive. 4. How many donor units should be screened to find the additional 1 unit ordered, plus 2 more to hold in reserve for the patient?

Explanation / Answer

12 more blood units must be screened in order to find the 3 more units.

Since out of 4, 1 contains e positive.

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