Q:- Random copolymers were used in some of the experimentsthat revealed the char
ID: 2124 • Letter: Q
Question
Q:- Random copolymers were used in some of the experimentsthat revealed the characterstices of the genetic code. For each ofthe following ribonucleotide mixtures, give the expected codons andtheir frequencies, and give the expected preportions of amino acidsthat would be found in a polypeptide dircted by the copolymer in acall-free, protein- synthesising system: a) 4 A : 6 C b) 4 G : 1 CQ:- Random copolymers were used in some of the experimentsthat revealed the characterstices of the genetic code. For each ofthe following ribonucleotide mixtures, give the expected codons andtheir frequencies, and give the expected preportions of amino acidsthat would be found in a polypeptide dircted by the copolymer in acall-free, protein- synthesising system: a) 4 A : 6 C b) 4 G : 1 C
Explanation / Answer
a)In this expt the ratio of the ribonucletides is 4A:6CSo if we see in the genetic code the following 8 codons will becoded: 1.CCC -proline 2.CCA - proline 3.CAC - histidine 4.CAA - glutamine 5.AAC - aspargene 6.AAA - lysine 7.ACC - threonine 8..ACA - threonine. Out of these 8 ,4 of them will be in a higher ratio thanthe other 4.they are: 1.CCC - proline 2.CCA - proline 3.CAC - histidine 4.ACC - threonine. As we can observe all of these codons have two Cs.As the concentration ofcytosine nucleotide is greater than the concentration of Adeninethese 3 respective amino acids will be observed morefrequently.Lysine,Aspargene and Glutamine will be observed ,but ina lesser frequency. b).Here the ratio is 4G:1C. So the codons are: 1.CGC - arginine 2.CGG - arginine 3.GCC - alanine 4.GCG - alanine 5.GGC - glycine 6.GGG - glycine 7.CCC - proline 8.CCG - proline so here the concentration of the nucleotides is 4G:1C. Therefore these codons which have two Gs will be more abundant.: 1.CGG - arginine 2.GCG - alanine 3.GGC - glycine 4.GGG - glycine So the frequency of these 3 amino acids will be more andproline will be very rare. hope this helps
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