Q1. Proton Travel 1 point possible (graded) Protons travel through which complex

Question

Q1.

Proton Travel

1 point possible (graded)

Protons travel through which complex of the ATP synthase?

Select ONE option:

A. Protons travel through the F1 complex.

B. Protons travel through the F0 complex.

C. Protons travel through both the F0 and F1 complexes.

Q2.

F0 Complex

1 point possible (graded)

If you need a refresher on membrane proteins, you can refer back to Lesson 1: Plasma Membrane and Membrane Proteins.

The F0 complex is composed of which of the following?

Select ONE option:

A. Integral membrane proteins

B. Peripheral membrane proteins

C. Both integral membrane and peripheral membrane proteins

Q3.

Cristae

3 points possible (graded)

The inner mitochondrial membrane contains a protein complex responsible for cristae formation. One of the mitochondria shown below has a genetic mutation and lacks these proteins.

PART 1: What is the difference between the two structures?

Select ONE option:

A. the outer membrane of the left mitochondrion has a larger surface area.

B. the inner membrane of the left mitochondrion has a larger surface area.

PART 2: Which mitochondrion do you predict has the mutation?

Select ONE option:

A. Left

B. Right

PART 3: Which mitochondrion would you expect to produce ATP more rapidly?

Select ONE option:

A. Left

B. Right

Q4.

Tetramethylrhodamine (TMR) is a positively-charged fluorescent dye that easily crosses lipid membranes. It specifically labels mitochondria in living cells, but it does not label the mitochondria of dead cells. The difference in labeling is directly due to:

Select ONE option:

A. differences in the reduction of complex I in the ETC.

B. the loss of the pH gradient across the inner mitochondrial membrane

C. differences in the levels of ATP between the two cells.

D. differences in the levels of pyruvate between the two cells.

Q5.

Mitochondrial Membrane Permeability

1 point possible (graded)

Which mitochondrial membrane is more permeable?

Select ONE option:

A. Inner mitochondrial membrane

B. Outer mitochondrial membrane

Q6.

Porins

1 point possible (graded)

Porin channels allow small molecules to flow across the:

Select ONE option:

A. Inner mitochondrial membrane

B. Outer mitochondrial membrane

Explanation / Answer

Answers

Q1. B. Protons travel through the F0 complex.

Reason: Basically F0 domain is the integral part of ATP synthase through which protons will travel along the gradient.

Q2. A. Integral membrane proteins.

Part 1. B. The inner membrane of the left mitochondrion has a larger surface area.

Reason: Due to folding of cristae in left mitochondrion surface area will be increased.

Part 2. Right (because of mutation, cisternae are invisible)

Part 3. Left (ATP synthesis takes place on the inner mitochondrial membrane)

Q4. B. the loss of the pH gradient across the inner mitochondrial membrane.

Reason: Inactive or dead mitochondrion has decreased membrane potential so the negatively charged dye fails to stain the dead mitochondrion.

Q5. B. Outer mitochondrial membrane.

Q6. B. Outer mitochondrial membrane.

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