Can u give a quick falsification of the incorrect answers and an explanation of

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Can u give a quick falsification of the incorrect answers and an explanation of the correct answer, thanks

ead: Lecture 24: Apoptosis Th Select: All None 1 Postís) in this T Message ActionsExpand All Collapse All posted 2 months ago (last ed Michael Munoz Lecture 24: Apoptosis Regarding apoptosis, which of the following statements is true? A. Excessive apoptosis is observed in Alzheimers and Parkinsons disease, and reduced apoptosis is observed in cancer cells. B. Apoptosis requires the activation of proteolytic enzymes known as caspases C. Apoptosis occurs during normal embryological development D. During apoptosis, enzymes hydrolyze the DNA, proteins, and phospholipids of the cell E. All of the above are true. Select: All None Messinge ActionsExpand All Colape Al 888 Fa F8 ? F3 3 5 8 TYU

Explanation / Answer

ans option E all of the above are true.

apoptosis comes from greek words apo means from and ptosis means falling. it is energy dependent biochememical mechenism of genetically programmed cell death process. Biochemical events lead to characteristic cell changes (morphology) and death. These changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, chromosomal DNA fragmentation, and mRNA decay. Between 50 and 70 billion cells die each day due to apoptosis in the average human adult. For an average child between the ages of 8 and 14, approximately 20 to 30 billion cells die a day.

A .NORMAL CELL undergoes regulated division differentiation and apoptosis but cancer cell lost the control over their division , differentiation and apoptosis. so that cancer cells reduces observed apoptosis.

B.The initiation of apoptosis is tightly regulated by activation mechanisms, because once apoptosis has begun, it inevitably leads to the death of the cell. The two best-understood activation mechanisms are the intrinsic pathway (also called the mitochondrial pathway) and the extrinsic pathway. The intrinsic pathway is activated by intracellular signals generated when cells are stressed and depends on the release of proteins from the intermembrane space of mitochondria. The extrinsic pathway is activated by extracellular ligands binding to cell-surface death receptors, which leads to the formation of the death-inducing signaling complex (DISC).

C. it is genetically programmed process of deliberate suside by an unwanted cell in a multicellular organism during embryogenesis, metamorphosis, and tissue turnover. for example differentiation of human finger in a developing embryo requires the cells between the fingers to initiate apoptosis so that the finger can separate.

D.yes DNA PROTEIN AND MEMBRANE IS DAMAGE DURING APOPTOSIS.

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