a) Which suspect presents a profile compatible to the sample found at the crime

Question

a) Which suspect presents a profile compatible to the sample found at the crime scene? Suspect #1 or Suspect #2

b) What information/s led to your conclusion in (a)? Give two pieces of evidence from the DNA profile to support your answer.

The crime was featured on BBC's Crimewatch program in December 2001 and North Wales Police received over 200 calls. Following reports of a teenager who had attacked a German student, the police went to the home of Matthew Hardman (suspect 1), who gave police a cheek swab. uring this visit, officers found a pai of Levi shoes. Forensic D Science Service (FSS) scientists matched Hardman's shoes to the footwear marks found at the murder scene. Prof ng suggested a much older offende so another suspect was also asked to give a cheek swab (suspect 2). Since both suspects were men, the officers needed to test fo other genetic differences. They focused on STRs (short tande r epeats), stretches of DNA that exist n all people, but in different numbers of repeats. Below is the STRs on chromosome #11 for both suspects and regions on othe chromosomes as shown by karyotype on the right. Chromosomes 11 of suspect Same pair in suspect 2 EH

Explanation / Answer

A) suspect #1

B) DNA Fingerprinting or DNA Typing is the method that uses VNTRs, including Mini satellites and microsatellites, to compare genomes of different person on the basis of the sequence of their base pairs. It is widely used for dtection of criminals, parents match etc.

Detection is based on unique RFLP patterns formed by the alleles of VNTRs.

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