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The table for the following three items. For a multiple-step reaction A - B - C#

ID: 253704 • Letter: T

Question

The table for the following three items. For a multiple-step reaction A - B - C# D A E - F, the Gibbs free energy changes and corresponding enzymes are listed in the following table. Reaction Catalytic Gibbs free Enzyme energy change (kJ/mol) AB' -1.0 B- C .. 2 -1.4 -1.4 CHD 1.0 DEE 4 -20.0 EFF 1.1 5 30. Which step is most likely to be regulated in cells? a. 1 b . 2 c.3 d) 4 e. 5 31. If enzyme 3 is inhibited, which of the following is false? a. molecule C will accumulate. b. molecule D will accumulate. c. molecule D will be depleted. d. molecule F will be depleted e. none of the above (32.)Process C - D is slightly unfavorable based on the standard Gibbs free energy change. However, it proceeds to the direction of producing D, because a. enzyme 3 makes the Gibbs free energy negative. b. enzyme 3 makes the Gibbs free energy more positive. c. product D is accumulated. d. product D is constantly removed. e. enzyme 3 is allosterically regulated.

Explanation / Answer

Answer-30 (d)-The negative free energy reactions are the rate-limiting step

Answer-31 (b)- If enzyme 3 is inhibited than molecule D will accumulate is the FALSE statement because if enzyme 3 is inhibited it will not convert molecule C into D, this will lead to depletion of molecule D, not its accumulation.

Answer-32 (d)- product D is constantly removed.

unfavorable reactions can be made favorable by pulling. In this case, for reactions where ?G°>0 (ie the reaction under standard conditions is unfavorable), the reaction can be made favorable by decreasing the concentration of products relative to reactants, such as by immediately using them in a subsequent, thermodynamically favorable reaction.

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