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a blackboard.towson.edu My LearnOnline-B... Towson University .. Chimes Providing Perry Hall, MD I Ap Bel Air North, MDI Question Completion Status: QUESTION 4 Regulatory transcription factors function by Oa promoting DNA replication Ob recruiting mediators or chromatin remodelers OC. directly recruiting RNA polymerase Od acting as mediators or chromatin remodelers QUESTION5 If you were to knockout a gene that functions as a histone deacetylase what effects would you expect in the cell? O a More DNA in the cell would be tightly wrapped around histones. Ob. Less DNA in the cell would be tightly wrapped around histones. O c. Transcription of certain genes would be enhanced. od Transcription of certain genes would be repressed. C e. Both a and d. f. Both b and c.

Explanation / Answer

Ans4:

Transcription regulatory factors function by binding to DNA and then recruiting other mediator molecules or chromatin modellers. This enhances/supresses transcription.

Ans 5: (f)

Both b&c.

Histone deacetylase plays role in tight wrapping of DNA around histone. If gene for this is knocked out, then DNA would be less tightly packed and transcription will be easy as DNA will be easily accessible.

B) recruiting mediators or chromatin remodelers

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