Chapter 13 1) Define the terms \"intron and exon. 2) Draw a diagram of the steps

Question

Chapter 13 1) Define the terms "intron and exon. 2) Draw a diagram of the steps involved in self-splicing of an RNA containing a group I intron 3) Describe the lariat mechanism of group Il intron splicing. ) Describe a model showing how nuclear pre-mRNA processing is coupled to transcription. 5) Describe a two-step model for transcription termination in eukaryotes. 6) Define the term "alternative splicing." Describe a specific example of alternative splicing. 7) Define the term "RNA editing" and discuss why the discovery of pan-editing events in trypanosomes at first seemed to shake the central dogma of molecular biology 8) Define the term RNA interference (RNAi). Compare and contrast key features of small interfering RNAs (SiRNAs) and micro RNAs (miRNAs).

Explanation / Answer

1. The non coding parts of a gene is called an intron while the coding part of a gene is called the exon. During transcription, entire gene is copied into pre mRNA which consists of exons and introns. Introns are removed thereafter by the process of RNA splicing, while exons are joined together to form a contiguous sequence. Exons codes for proteins while introns do not.

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