can you help me with number 12? o the enzyme whose activity is shown in this gra

Question

can you help me with number 12?

o the enzyme whose activity is shown in this graph? 40 30 20 10 0 50 100 150 200 250 300 Substrate (mm) A) 30 mM ) 60 mM C) 200 mM D) cannot be determined from the information given 11. Of the following pairs of amino acids, which pair is most likely to stabilize the tertiary structure of a folded protein? A) Lys and Arg B) Cys and Glu CGlu and Lys D) Gln and Glu 12. Th of the protein is rich in Leu, Val, Phe, and other hydrophobic amino acids and th protein interior is rich in charged and polar amino acids. What is the most likely e 3-D x-ray crystallography structure of a protein reveals that the surface biological role of this protein? B it is likely to be a cell-surface protein exposed to the extracellular environment B) it is likely to be a soluble cytosolic protein C) it is likely to be a monomer D) it is likely to be an integral membrane protein (ie, a transmembrar protein)

Explanation / Answer

ANSWER 12
Options A), B) and C) suggest environments where exterior hydrophobic amino acids are being made to tolerate an aqueous environment. This is not an energetically favourable state. The only option that accounts for the exterior of the protein in a like-minded hydrophobic environment is:
D) it is likely to be an integral membrane protein, (ie, a transmembrne protein)

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