Steroid hormones can diffuse into all cells of the body; however, not all cells

Question

Steroid hormones can diffuse into all cells of the body; however, not all cells respond to steroid hormones. Why?

Not all cells contain the genes necessary to respond to steroid hormones. Not all cells are lipid soluble and therefore they cannot respond to steroid hormones. Only cells displaying plasma membrane receptors can respond to a lipid-soluble hormone. Only cells with surface protein receptors can respond to steroid hormones. Only cells containing cytoplasmic or nuclear receptors to the steroid hormone can respond.

Explanation / Answer

Only cells containing cytoplasmic or nuclear receptors to the steroid hormone can respond.

Receptors for steroid hormones are located inside the target cell, in the cytoplasm or nucleus and these receptors function as ligand dependent transcription factors.

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