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Below are characteristics of intracellular pathogens that are not killed by the

ID: 264123 • Letter: B

Question

Below are characteristics of intracellular pathogens that are not killed by the host phagolysosome. These pathogens use one of three mechanisms to accomplish this. They can escape the phagosome, inhibit phagosome-lysosome fusion, or grow inside the phagolysosome. Determine which characteristics describe pathogens that use one of these mechanisms.

Characteristics (9 items) (Drag and drop into the appropriate area below)

Prefer acidic conditions

Inhibit endosome trafficking

Live in a vesicle-like structure with destructive molecular species

Include Shigella and Listeria

Use Hemolysins

Include Coxiella

Include Salmonella and Legionella

Live in a vesicle-like structure without destructive molecular species

Live in the Cytoplasm

MECHANISMS:

Escape Phagosome:

Prevent Fusion:

Grow in Phagolysosome:

Explanation / Answer

Below are characteristics of intracellular pathogens that are not killed by the

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