30. How would application of a Ca2+ channel blocker affect the function of a syn

ID: 271390 • Letter: 3

Question

30. How would application of a Ca2+ channel blocker affect the function of a synapse?

a. It would increase the magnitude of postsynaptic potential.

b. It would decrease the magnitude of postsynaptic potential.

c. It would eliminate the postsynaptic potential but have no effect on presynaptic neuron.

d. It would eliminate the postsynaptic potential and the presynaptic Ca2+ current.

32. The most important factor determining whether a receptor-operated ion channel is inhibitory or excitatory is

a. the ligand-binding properties of the receptor.

b. whether the permeant ion is positively or negatively charged.

c. whether the permeant ion’s reversal potential is positive or negative to threshold.

d. the number of different ions that can pass through the receptor.

30.

Ca+2 channel helps in the release of neurotransmitter. Neurotransmitter in turn causes post-synaptic potential.

So if Ca+2 channel blocker is used, it prevents the release of neurotransmitter. This in turn would decrease the magnitude of postsynaptic potential.

Hence option "b" is the correct answer.

32.

Receptor-operated channel is a receptor protein, which has an ion channel as its strucure.

The ligand binding to the receptor operated channel makes it either excitory or inhibitory in its function.

Thus option "a" is the correct answer.

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