In the late 1800s, a researcher by the name of Robert Koch developed a series of
ID: 300037 • Letter: I
Question
In the late 1800s, a researcher by the name of Robert Koch developed a series of postulates (guidelines) that can be used to prove that a given pathogen is the true cause of a disease.
Koch's Postulates
1. The suspected causative agent must be found in every case of the disease and be absent from healthy hosts.
2. The agent must be isolated and grown outside the host.
3. When the agent is introduced to a healthy, susceptible host, the host must get the disease.
4. The same agent must be found in the diseased experimental host.
Which of the following steps does NOT follow one of Koch's postulates?
Pick step that does NOT follow the postulates.
You are able to isolate a pathogenic bacterium from someone with a new type of pharyngitis. You collect a throat swab from a family member who has also become sick. A mouse that was exposed to a potential viral pathogen has died and you are able to isolate the virus from the liver of the mouse. You give a patient an antibiotic to treat an infection.Explanation / Answer
Answer: You give a patient an antibiotic to treat an infection.
Reason:
If you give a patient an antibiotic to treat an infection and it may inhibit the growth of microbial species but may not reduce the pathological effects produced in the host, may fail to follow one of Koch's postulates (because same agent must be found in the diseased experimental host). Pharyngitis is mainly due to either bacterial (strep throat) or viral infections caused by cold, influenza infections. In the above given postulates, it may be possible to follow "fourth postulate" of Koch i.e. "the same infectious agent must be found in the diseased experimental host". It is reliable and possible when you collect a throat swab from a family member other who actually infected with infection & from the family member who has also become sick.
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