Below is a sequence of a gene which contains five of the 54bp repeats: TCCTATCAC

Question

Below is a sequence of a gene which contains five of the 54bp repeats:

TCCTATCACA GGCTGGAAGC AATAAGACAG CTCAAAATTT TATGACACTA CCAGAATGGC TGACAATTTT AAACTTATGA ACTGTTTATT TCTGGAATTT TCCATTTACT ATTTTTGGAC CTTGGTTGAC CACAGGTAAC TGAAACTACA GAAAGCAAAA CCATGAATAA AGGAGGACTA CTGTATTTTG TGATAAGAAG ATTAAAGTGT CTTTTCATGT GCCCTTACTT TCTAGCAGTG TGTTACAGGC AACAATGGCA GTGAGAGCAG TCCTGCTACT ACCGGTGCAC TGTCCACGGG GTCACCTCCC AGGGAGAATC CATCCCATCC TACTGCCAGC GCTCTGTCCA CAGGATCGCC TCCCATGAAG AATCCATCCC ATCCTACTGC CAGCGCTCTG TCCACAGGAT CGCCTCCCAT GAAGAATCCA TCCCATCCTA CTGCCAGCAC ACTGTCCATG GGATTGCCTC CCAGCAGGAC TCCATCCCAT CCTACTGCCA CTGTTCTGTC CACGGGGTCA CCTCCCAGCG AATCCCCATC CAGAACTGGT TCAGCAGCAT CAGGTAGTGG ATCAGGACAA CTAATGTTTC AAACTCCAAT GCCAGACATT CACTATGTGC TGAGCTCTCA CTGTGTGCCC CAGGCACTGA TGTGGAAGTA CAAGGTTTTT TTTTCTTTTT CCCTTTTTCC TTTTTGTCAG GTATATTGGG GTATATTTAT ACACAATAAA ATTCACCAGT TTGAGGGGTA CAAACAAGAA TTCTGACAGA TGTGTACCTT AGTGTAAGCG CTACCACAAT CACCATA

Each of the imperfect 54bp repeat sequences ends in the sequence 'CCATCC'. What is the exact sequence of the 1st of the imperfect 54bp repeat sequences?

Explanation / Answer

Answer: Imperfect repeats sequences are minisatellite repeat sequences which varies between 10-60 nucleotides or base pairs. Imperfect repeats can be highly variable but can be recognised, thus are called divergent repeats.

The exact sequence of the first imperfect 54bp repeat is underlined in the sequence below:

TCCTATCACA GGCTGGAAGC AATAAGACAG CTCAAAATTT TATGACACTA CCAGAATGGC TGACAATTTT AAACTTATGA ACTGTTTATT TCTGGAATTT TCCATTTACT ATTTTTGGAC CTTGGTTGAC CACAGGTAAC TGAAACTACA GAAAGCAAAA CCATGAATAA AGGAGGACTA CTGTATTTTG TGATAAGAAG ATTAAAGTGT CTTTTCATGT GCCCTTACTT TCTAGCAGTG TGTTACAGGC AACAATGGCA GTGAGAGCAG TCCTGCTACT ACCGGTGCAC TGTCCACGGG GTCACCTCCC AGGGAGAATC CATCCCATCC TACTGCCAGC GCTCTGTCCA CAGGATCGCC TCCCATGAAG AATCCATCCC ATCCTACTGC CAGCGCTCTG TCCACAGGAT CGCCTCCCAT GAAGAATCCA TCCCATCCTA CTGCCAGCAC ACTGTCCATG GGATTGCCTC CCAGCAGGAC TCCATCCCAT CCTACTGCCA CTGTTCTGTC CACGGGGTCA CCTCCCAGCG AATCCCCATC CAGAACTGGT TCAGCAGCAT CAGGTAGTGG ATCAGGACAA CTAATGTTTC AAACTCCAAT GCCAGACATT CACTATGTGC TGAGCTCTCA CTGTGTGCCC CAGGCACTGA TGTGGAAGTA CAAGGTTTTT TTTTCTTTTT CCCTTTTTCC TTTTTGTCAG GTATATTGGG GTATATTTAT ACACAATAAA ATTCACCAGT TTGAGGGGTA CAAACAAGAA TTCTGACAGA TGTGTACCTT AGTGTAAGCG CTACCACAAT CACCATA

Therefore the exact sequence of the first repeat is:

CCTGCTACT ACCGGTGCAC TGTCCACGGG GTCACCTCCC AGGGAGAATC CATCC

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