easy stats question Sickle cell disease is an inherited disorder of the red bloo

Question

easy stats question

Sickle cell disease is an inherited disorder of the red blood cells that in the United States aects mostly blacks. It can cause severe pain and many complications. Can the drug hydroyurea reduce the pain caused by sickle cell disease? A study by the National Institutes of Health gave the drug to 150 sickle cell suerers and a placebo to another 150. The researchers counted the episodes of pain reported by each subject”. (a) Identify the experimental units or subjects, treatments, the factors, and the response variable in this design. (b) It might seem more humane to give all the subjects hydroxyurea in the hope it will help them. Why would this not provide any information about the drug eectiveness?

Explanation / Answer

Answer :

   (a)

Subjects: 300 sickle cell patients.

Factor: drug given.

Treatments: hydroxyurea and placebo.

Response variable: number of pain episodes.

(b)

In fact, the experiment was stopped ahead of schedule because the hydroxyurea group had only half as many pain episodes as the control group. Ethical standards require stopping the experiment as soon as significant evidence becomes available.

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