In the book Brain on Fire, the author started having paranoid delusions when her

Question

In the book Brain on Fire, the author started having paranoid delusions when her body's immune system attacked her NMDA receptors and destroyed them. Which of the following is true based on this account? A) The Dopamine hypothesis o schizophrenia is correct. B) Tonic activation of inhibitory interneurons expressing NMDA receptors is important in preventing delusions C) Ketamine would have worked well for the author to stop the delusions. D) Loss of NMDA receptors causes neurons to transport more AMPA receptors to the cell membrane and thus become overexcitable. Save Question 38 (1 point) When glutamate is released at a synapse and the postsynaptic cell is already depolarized, what happens? A) Nothing happens B) The magnesium ion blocking the NMDA receptor at resting potential will be removed, and calcium ions will flow into the postsynaptic cel . C) The NMDA receptor, which is inhibitory when activated, will reduce the level of depolarization D) None of the above

Explanation / Answer

This had actually led to number of discoveries and mostly related to the schizophrenia. It was also observed that many adults with anti-NMDAR encephalitis also was seen to suffer from schizophrenia.

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