Albinism is a condition where individuals can\'t make melanin pigment. The affec

Question

Albinism is a condition where individuals can't make melanin pigment. The affected gene encodes for tyrosine aminotransferase, a key enzyme in melanin production. If you analyze the DNA of an albino individual, of the following mutations, which one is the least likely mutation responsible for the albino phenotype?

Albinism is a condition where individuals can't make melanin pigment. The affected gene encodes for tyrosine aminotransferase, a key enzyme in melanin production. If you analyze the DNA of an albino individual, of the following mutations, which one is the least likely mutation responsible for the albino phenotype? A.A substitution of A to G at 3 splicing site o B. A deletion in the TATA box region. o C. An insertion after the start codon D. An extra stretch of TTAATT in intron 1.

Explanation / Answer

least likely mutation in albinism is D) an extra stretch of TTAATT in intron 1.

There are 5 types of albinism ,the most common ones are OCA1 and OCA 2 .In OCA1 there is amutation in Tyr gene,that produces the enzyme tyrosinase

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