A clinical microbiology laboratory compared the frequency of isolation of DNA hy

Question

A clinical microbiology laboratory compared the frequency of isolation of DNA hybridization probe to a culture method for the sexually transmitted bacterium Neisseria gonorhaeae. The frequency of isolation from clinical specimens was historically 10%. The lab ran 100 split samples, and the results are presented in the table below. (20 pts) Table. Comparisonofthe Distribution of Negate and Positive Resultsforthe DNA Probe and Culture Methods. 2- Culture Results DNA Probe Results Positive Negative Positive Negative 9 2 1) 2) Calculate the positive predictive value? Calculate the negative predictive value?

Explanation / Answer

Solution:

From the given table, we have

A = 9

B = 2

C = 1

D = 88

Positive Predictive value = [A/(A+B)]*100

Positive Predictive value = [9/(9 + 2)]*100 = (9/11)*100 = 0.8182*100 = 81.82%

Positive Predictive value = 81.82%

Negative Predictive Value = [D/(D+C)]*100

Negative Predictive Value = [88/(88+1)]*100 = (88/89)*100 = 0.9888*100 = 98.88%

Negative Predictive Value = 98.88%

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