A series of mutations in a bacterium results in the requirement of either trypto

Question

A series of mutations in a bacterium results in the requirement of either tryptophan orsome related molecule in order for growth to occur. From the data shown here, suggest a biosynthetic pathway for tryptophan. (Yes indicates growth of mutant strain on growth media supplement. No, indicates inability to grow on growth media supplement).

Minimal

Media

Indole

Indole

Glycerol

Phosphate

Mutation

Minimal

Media

Indole

Indole

Glycerol

Phosphate

Anthranilic Acid Tryptophan trp-8 no yes yes yes yes trp-2 no yes yes no yes trp-3 no yes no no yes trp-1 no no no no yes

Explanation / Answer

The tryptophan biosynthetic pathway
Trp biosynthesis is a biologically expensive, complicated process. In
fact, the products of four other pathways are essential contributors of carbon
or nitrogen during tryptophan formation. Thus, the principal pathway
precursor, chorismate, is also the precursor of the other aromatic amino
acids, phenylalanine and tyrosine, as well as serving as the precursor of paminobenzoic acid and several other metabolites. In addition, glutamine,
phosphoribosylpyrophosphate, and L-serine contribute nitrogen and/or
carbon during tryptophan formation

Related Questions

Navigate

• Browse (All)
• Browse A
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.