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A test was used to screen for autism in 2,500 children with diagnosed autism and

ID: 3376462 • Letter: A

Question

A test was used to screen for autism in 2,500 children with diagnosed autism and in 5,000 age- and race-matched control children. The results of the screening test were positive in 1,800 cases and in 800 control children, all of whom had not been diagnosed with autism.

Autism

No autism

Total

Positive screening test

1,800

800

2,600

Negative screening test

700

4,200

4,900

Total

2,500

5,000

7,500

What is the sensitivity of the autism screening test?

What is the specificity of the autism screening test?

What is the positive predictive value of the autism screening test?

What is the negative predictive value of the autism screening test?

Autism

No autism

Total

Positive screening test

1,800

800

2,600

Negative screening test

700

4,200

4,900

Total

2,500

5,000

7,500

Explanation / Answer

1) sensitivity of the autism screening test=true positive/total autistic =1800/2500=0.72

2)specificity of the autism screening test =true negative/no autistic =4200/5000=0.84

3) positive predictive value of the autism screening test =true positive/total psoitive=1800/2600=0.6923

4)negative predictive value of the autism screening test=true negative/total negative =4200/4900=0.8571

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