Assume the pulse chase experiment was performed on pancreatic cells of Frank and
ID: 34375 • Letter: A
Question
Assume the pulse chase experiment was performed on pancreatic cells of Frank and Lily and results are as following;
FRANK:
Time
ER
Golgi
Cytoplasm
Lysosomes
Extracellular Space
3 min
162
7
21
5
4
20 min
160
7
17
6
8
60 min
160
7
14
6
13
120 min
170
7
18
6
10
LILY:
Time
ER
Golgi
Cytoplasm
Lysosomes
Extracellular Space
3 min
162
162
21
5
4
20 min
73
160
17
6
8
60 min
9
160
14
6
13
120 min
11
170
18
6
10
Question #3:
Explain what exactly is going on with Frank and Lily
Time
ER
Golgi
Cytoplasm
Lysosomes
Extracellular Space
3 min
162
7
21
5
4
20 min
160
7
17
6
8
60 min
160
7
14
6
13
120 min
170
7
18
6
10
Explanation / Answer
Comparing the above results we can notice that the amount of secretions released from the Golgi complex of pancreatic cells in Frank is very low than in Lily. This indicates the inability of Frank to produce sufficient quantity of insulin hormone required by the body. Hence we can conclude that Frank is suffering from Type 1 diabetes.
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