Proteins such as the ß amyloid and the mutant ß amyloid that results in early-on

ID: 3473777 • Letter: P

Question

Proteins such as the ß amyloid and the mutant ß amyloid that results in early-onset Alzheimer’s differ from one another because:

A.Peptide bonds linking the amino acids differ from one protein to another.

B.The two proteins have a different combination of amino acids along the chain of the polypeptide.

C.Presence of the element N is only found in one protein.

D.The two proteins each contains their own unique types of amino acids.

E.The number of amino acids in the chains differ.

Which of the following amino acids might you NOT expect to find in the intra-membrane region of the ß-APP protein?

A.valine

B.alanine

C.serine

D.aspartate

Which amino acid change in the ß-amyloid protein fragment would be most likely to make it stick together?

A.Replacing an amino acid with a hydrophilic R-group with one that is hydrophobic.

B.Replacing an amino acid with a hydrophobic R-group with one that is even more hydrophobic.

C.Replacing an amino acid with a hydrophobic R-group with one that is hydrophilic.

D.Replacing an amino acid with a hydrophilic R-group with one that is even more hydrophilic.

- B.The two proteins have a different combination of amino acids along the chain of the polypeptide. Valine is substituted for glycine.

- intramembrane region will have hydrophobic amino acids: aspartate is charged.

- B.Replacing an amino acid with a hydrophobic R-group with one that is even more hydrophobic through hydrophobic interactions.

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.