Complete each sentence to demonstrate your knowledge of the events that occur at

Question

Complete each sentence to demonstrate your knowledge of the events that occur at inhibitory chemical synapses At an membrane allow influx of channels specific for those ions. chemical synapse, activated receptors on the postsynaptic inhibitory or efflux of through Cl In cells that actively transport Cl-out of the cell, the ECI is more the resting membrane potential than hyperpolarization Therefore, as Ci channels open, Cl enters the cell, producing a called an leave However, in cells that do not actively transport C, the Eci is resting membrane potential. the inhibitory postsynaptic potential Therefore, a rise in C permeability does not change the membrane potential, but it makes it more difficult for other ion types to change the potential by the membrane at the resting level. K+ Finally, with increased K+ permeability, more K+ ions membrane moves closer to the EK, causing an IPSP equal to the cell and the stabilizing negative

Explanation / Answer

At an inhibitory chemical synapse, activated receptors on the post synaptic membrane allow influx of chloride ions or efflux of potassium ions through channels specific for those ions.

In cells that actively transported chloride ions out of the cell, ECl is more negative than the resting membrane potential

Therefore, as chloride channels open, chloride ions enter the cell producing a hyperpolarisation known as inhibitory post synaptic potential

However in cells that do not actively transport chloride ions Ecl is equal to the resting membrane potential.

Therefore, a rise in Cl permeability does not change the membrane potential but it makes it more difficult for other ion types to change the potential by stabilizing the membrane at the resting level

Finally with increased K permeability, more K ions leave the cell and membrane moves closer to the Ek causing an IPSP.

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