Complete each sentence to correctly describe a step that occurs during skeletal

Question

Complete each sentence to correctly describe a step that occurs during skeletal muscle EC coupling, then click and drag the steps into the proper order. Drag the text blocks below into their correct order Energized portions of myosin molecules called bind to actin. ryanodine receptors troponin dihydropyridineCross-bridge binding triggers the release of ATP hydrolysis products from Ca2 receptors , and produces the which generates force. cross-bridges || . reticulum sarcoplasmic binds to myosin, breaking the linkage between actin and myosin and thereby allowing the cross-bridges to from actin. relaxes actin Cytosolic Ca decreases as actively transport Ca2 back into Ca2-ATPases myosin ATP bound to myosin is another round of cross-bridge cycling occurs as long as Ca2 remains bound to , energizing the cross-bridge, and tropomyosintroponin. These channels are embedded within the membrane of the sarcoplasmic reticulum, and when they are open, they allow the release of hydrolyzed on the thin filaments, causing tropomyosin to Ca2 binds to move away from its blocking position, thereby uncovering cross-bridge binding sites on dissociate ATP Action potentials that propagate along the T-tubules induce membrane proteins called power stroke to pull open channels that are called Finally, removal of troponin restores the blocking position , the cross-bridge cycling ceases, and the skeletal muscle fiber

Explanation / Answer

1.Energised portion of myosin molecules called cross-bridges binds to actin

2.Cross bridge triggers the release of ATP hydrolysis products from Myosin and produces the power stroke which generates force

3. ATP binds to myosin, breaking the linkage between actin and myosin thereby allowing cross brides to dissociate from actin

4.Cytosolic Ca2+ decreases as Ca2+ ATPase actively transport Ca 2+ back into the sarcoplasmic reticulum

5 ATP bound to myosin is hydrolyzed, energizing the cross bridge and another round of cross-bridge occurs as long as Ca2+ remains bound to troponin

6.These channels are embedded within the membrane of sarcoplasmic reticulum, and when they are open, they allow the release of Ca2+ from terminal cisternae

7.Ca2+ binds to troponin on thin filaments, causing tropomyosin to move away from its blocking position thereby uncovering cross-bridge binding sites on actin

8.Action potentials that propagate along the membrane T tubule induce membrane proteins called dihydropyridine receptors and pull open channels called ryanodine receptors

9..Finally, the removal of Ca2+ from the troponin restores the blocking position of tropomyosin, the cross-bridge cycling ceases and the skeletal muscle fibre relaxes

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