Case 2: The Bloated Mrs. Blanc Your next call is to the home of Mrs. Blanc. As b

Question

Case 2: The Bloated Mrs. Blanc Your next call is to the home of Mrs. Blanc. As before, you have three witnesses to interview Witness statemsents Ms. Magenta. "Berween you and me, she's really let herself go. She has fat deposits like around her face and trunk, and a weird hump on her back. If you ask e, se goodt" in all of these strange places et eef Cot Lmut -Not that I want to alk about soch things, but she's seemed blouted. a told me that her blood pressure has gone up!" Ms. Feather: "The poor dear. She's been sick immune system needs boosting, But my herbal teas don't seem to help.- so much lately with all kinds of infections. Personally, I think her What are your initial thoughts, based upon the witnesses' statements? Does one hormone produce these effects? come to mind that could our next step is to speak with Mrs. Blanc. During the interview you notice a bottle of pills on her nightstand. You log the pills as evidence and send them off to the lab for analysis. The lab report shows the prednisone, which you know to be a glucocorticoid similar to the hormone cortisol. Is this pills to be the medication why not? hormone cortisol. Is this finding significant? Why 16 Based upon the witness statements and the laboratory analysis, what is your final diagnosis? Explain your reasoning 436 Exploring Anatomy& Physiology in the Laboratory

Explanation / Answer

Ans-1

I think it is hormone cortisol or glucocorticoid which is elevated in cushing disease so in our witness statements we see symptoms of this disease.The first sign of this condition is usually weight gain around the trunk and in the face.Individuals with cushing disease can develop a hump on their upper back caused by abnormal deposits of fat.They also have a weakened immune system and are at an increased risk of infections.

Ans-2

Medications like prednisone, have the same effect in the body as does cortisol produced by your body. Many of patient taking steroid unknowingly for minor inflammatory problems and become habit of cortisol or other steroidal Drugs, so this finding is not good.

Ans-3

Based on the all evidence, the patient is finally diagnosed as exogenous Cushing's syndrome due to chronic use of prednisolone unknowingly.

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