When Tina went to the doctor for a checkup everything was normal, although her b

Question

When Tina went to the doctor for a checkup everything was normal, although her blood pressure had dropped compared to her last checkup one year ago. Her mean arterial pressure (MAP) was 105 mmHg compared to 125 mmHg a year ago. Determine what effect this MAP change will have on Tina's glomerular filtration rate (GFR). Assume autoregulation in the kidney has taken place.

Question 5 options:

Tina's GFR will have increased.

Tina's GFR will have decreased.

There would be no change in Tina's GFR.

Tina's GFR will have increased.

Tina's GFR will have decreased.

There would be no change in Tina's GFR.

Explanation / Answer

Right option is TINA'S GFR WILL HAVE INCRASED.

Relation betdween Blood presure vs GFR

. In the nephron (basic unit of renal system), the structure called juxtaglomerular apparatus. This JGA structure contain stretch receptors, which signal JGA to secret renin.

Renin is the one of main enzyme will convert into angiotensin which is produced and stored in the kidney. The function of angiotensin is vasoconstriction.

Whenever GFR rate is decreases, stretch receptors secret renin which is converted into angiotensin leads to vasoconstriction. Finally vasoconstriction will increase peripheral resistance leads to elevated BP.

If GFR level increases, leads to vasodilation will cause ddecrease peripheral resistance and low blood pressure.

So, Tina's increased GFR only the reason for the low blood pressure.

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