In class we discussed blood doping issues. Now assume that the normal hematocrit
ID: 3516404 • Letter: I
Question
In class we discussed blood doping issues. Now assume that the normal hematocrit of an athlete is 40. The athlete has a normal blood volume of 5 liters. Just prior to a major competition four 250 ml units of the athlete's own packed red cells that have been donated and cryopreserved over the past two years are transfused. What do you anticipate wl be the major effects on the athlete? Quantify your answer to the extent that you are able. How could blood doping affect an athlete's potential performance level and alter his/her physiological state to cause a health endangerment? Consider the effects of blood doping on cardiac output and the work done by the heart in pumping blood through the circulatory system during high stress exercise. How would you approach developing biotransport models to predict quantitatively both of the above phenomena? You should develop a convincing argument concerning risks to the cardiovascular system arising from blood doping. It would be most effective to develop some model data that can be presented to illustrate quantitatively the consequences of manipulating the hematocrit upwards to varying extents. In addition to potential alterations to the stress level on the cardiovascular system, what are the other physiological effects of blood doping? Why would an athlete use blood doping? What are the tradeoffs to consider in whether to engage in using blood doping techniques?Explanation / Answer
The major effects of blood doping are increased cardiovascular performance and increased oxygen delivery to tissues during need or performing.Blood doping increases blood viscosity with increased heart rate, blood pressepr, viscosity, causing insufficiency, renal damage, hepatic damage and other rist leading to endangerment.
The cardiac output and work done both will increase. There is a increase in LV pressure and volume increasing cardiac work the viscosity if blood is also increased.
It causes risk of infections, kidney danage, headache, edema and various other complications.
Atheletes would use blood doping to cheat at competitions in the form of cryopreserved or using hormones like EPO that increase blood count. So they may cause a reason behind cheating and are non negligible.
Blood doping technique can be good for treating patients with severe anemia, trauma and ither requirements however their use in activities like atheletes doping is the limiting feature.
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