Complete the following sentences: a. Strain sensing by the thick-filament in the

ID: 3518528 • Letter: C

Question

Complete the following sentences:

a. Strain sensing by the thick-filament in the heart is hypothesized to be a molecular mechanism underlying __________

b. Omecamtiv mecarbil accelerates _________ step in the actomyosin ATPase cycle.

c. Mutations in MYH7 causes 15% of all cardiomyopathies. ________ is another sarcomere protein that is also most commonly altered in cardiomyopathy.

d. Mutations in the mesa are hypothesized to cause HCM and DCM by altering interactions between the masa surface and _______

a. cellular level

At this level, heart muscel cells generate higher force when stretched.

b. rate limiting step

It is seen in over all cycle.

c . MYBPC3

It is the other sarcomere protein.

d . myosin binding surface.

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