Cell Biology Please Need Help With Problem ( Part 2) Please and Thank you in adv

Question

Cell Biology

Please Need Help With Problem ( Part 2)

Please and Thank you in advance!

Figure below shows how normal signaling works with a Ras protein acting downstream of an RTK. You examine a cell line with a constitutively active Ras protein that is always signaling. Will each of the following conditions turn off signaling in this cell line? Explain why. A. addition of a drug that prevents protein X from activating Ras B. addition of a drug that increases the affinity of protein Y and Ras C. addition of a drug that blocks protein Y from interacting with its target D. addition of a drug that blocks the constitutively active Ras protein

Explanation / Answer

Answer: the signalling needs the function of the series of all the steps, if one step donot function, it signalling will not takes place.

A) The addition of the drug that prevents protein X will lead to turnoff signaling

B) The addition of the drug that increase the affinity of protein Y and Ras will increase signal

C) Blocking protein Y will turnoff signalling

D) Drug that block Ras proteins also will turnoff the signaling.

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