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Reread Case Studies 2 (found prior to Chapter 9), 3 (found prior to Chapter 12),

ID: 41995 • Letter: R

Question

Reread Case Studies 2 (found prior to Chapter 9), 3 (found prior to Chapter 12), and/or 4 (found prior to Chapter 21) and answer the questions below. You must answer at least 3 of the questions below. You may answer all 3 questions from the same case (preferred) or you can mix and match 3 questions for multiple case studies. You can answer more than 3 questions, but you must answer at least 3 for full credit. The answers to these questions can be found in the chapters following each case study. You must answer the questions in your own words. Please indicate which questions you are answering. Type your answers in a word document and submit your answers to the appropriate DropBox on D2L. Due: 23 Apr. 2015, 11:59 PM How can doctors test for the spread of cancer? How do cancer cells spread throughout the body? What genes arc involved in cancer? What can your personal genome tell you about your genetic risk factors? How do genetic tests identify disease risk factors? How can the Y chromosome be used to trace ancestry? How can mitochondrial DNA be used to trace ancestry? What genetic differences have made some individuals more and some less susceptible to malaria? How did malaria come to infect humans? What human genes arc under selection for resistance to malaria?

Explanation / Answer

case study 2;

1. How can docotors test for spread of cancer ?

answer; the spread of disease is called metastastis . the doctors detect through staging and is clinical stage which can be detected by the in spread in the body , futhur through the biopsy

2. how do cancer cells spread thought the body ?

answer ; spread through the metastasis , uncontrolled proliferation through the blood stream in lymphoma

3. which genes are involved in cancer?

answer;   the genes invloved is mutation in P 53 gene ,   BRAC1 gene , BRAC2 gene . P53 is a tumour supressor gene and protooncogenes when there are any mutations in these genes they cause cancer

case study 3;

1. what can your genome tell you about your genetic risk factors ?

answer;   it can tell about the risk of having the genetic diorders due to mutation in the gene . genetic disorders such as cystic fibrosis , hugstons disease

2. how do genetic tests identify disease risk factors?

any mutation in genetic these risk factors will increase the risk of having genetic disase , so the gentic tests will identify these diseases preventing them from expression of the gene

3. how can the y chromosome be used to trace ancestry ?

it show s the paternal ancestary of the , as the y -chromosome is present only in males it will not change from generation to generation , bacause the men will have same Y chromosome where that is passes from ancestry the genome consists of XY . so it wont change , so y chromosome is used to trace the ancestry

CASE STUDY 3;

1.WHAT GENETIC DIFFRENCES HAVE MADE SOME INDIVIDUALS MORE AND SOME LESS SUSCEPTIBLE TO MALARIA/

theres is a specific genetic change in the genome of the individual which produces the heamoglobin molecule which produces the enzyme which inhibhits the growth of plasmodium as plasmodium uses the host cell machinary for its replication

2.how did malaria come to infect humans ?

it is though the intermediate host the mosquito which carries the plamodium only female anphalus mosquitos

3.. what human genes are under selection for resistance to malaria ?

heamoglobin genes

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