How are proteins like GPCR transported into the endoplasmic reticulum..? So i kn

Question

How are proteins like GPCR transported into the endoplasmic reticulum..?

So i know that protein translocation occurs cotranstionaly.

As mRNA is traslated by ribosome the ER signal sequence is made on growing polypeptide. The signal sequence is then bounded by a signal recognition particle (SRP) ultimately stopping the ribosome translation. The signal sequence bound with SRP moves toward the membrane of ER and binds to another receptor SRP. Once the SRP receptor binds the Signal recognition particle is removed and recycled. Then SRP receptor takes the complex of protein and ribosome to translocation channel in ER membrane. The protein will start to fed through this translocation channel. Inside the ER the signal sequence will be cleaved by the signal peptidase.

IS THIS HOW GPCR (G PROTEIN COUPLED RECEPTOR) - 7 TRANSMEMBRANE PROTEIN ENTERS THE ENDOPLASMIC RETICULUM?

Explanation / Answer

yes , this is the way how GPCR protein is translocated.

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