34) Which of the following is true regarding pharmaco-mechanical coupling? A) It

Question

34) Which of the following is true regarding pharmaco-mechanical coupling?

A) It is the primary mechanism by which cardiac muscle contractility is altered.

B) It allows for smooth muscle contraction without generation of action potentials.

C) It is independent of changes in cytoplasmic Ca2+.

D) It is characterized by the opening of voltage-gated Ca2+ channels in smooth muscle.

32) The correct sequence of events at the neuromuscular junction are:

A) action potential in the motor neuron, depolarization of the motor end plate, opening of voltage-gated Ca2+ channels in the motor neuron, release of acetylcholine from synaptic vesicles.

B) opening of voltage-gated Ca2+ channels in the motor neuron, release of acetylcholine, depolarization of the motor end plate, breakdown of acetylcholine by acetylcholinesterase.

C) release of acetylcholine, action potential in the motor nerve, action potential in the muscle, breakdown of acetylcholine by acetylcholinesterase.

D) opening of voltage-gated Ca2+ channels in the motor neuron, action potential in the motor end plate, action potential in the muscle, release of acetylcholine.

Explanation / Answer

34) Which of the following is true regarding pharmaco-mechanical coupling?
B) It allows for smooth muscle contraction without generation of action potentials.

pharmacomechanical coupling, account for physiological mechanisms which can regulate contraction of smooth muscle independently of the potential of membrane

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