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In using bioinformatics tools to search for possible protein-coding genes in the

ID: 50644 • Letter: I

Question

In using bioinformatics tools to search for possible protein-coding genes in the DNA sequence of the human genome, which of the following would be good evidence for a region being genic?

A) Presence of the DNA sequences that demarcate introns
B) Presence of a long (100 bp or more) ORF flanked by a “start” and “stop” codon
C) Presence of an ATG codon (since the “start” codon is invariably ATG)
D) A and b
E) B and c

This question has already been asked but the answers given were conflicting. Please help!

Explanation / Answer

D) A and b

As organism’s DNA is analyzed for a particular coding genes of protein it'd be higher to demarcate introns such coding sequence will be simply known. in a very organism DNA each introns and exons exist endlessly. If desoxyribonucleic acid sequence of associate degree organism is compared to protein factor than the analysis ends up in false result. The presence of begin and stop sequence clearly indicates the coding sequence. Thus, simply factor will be known. Hence, each A and B choices facilitate in higher analysis of protein coding genes in human by victimization bio-informatics tools.

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