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1. ________ is the histological procedure in which a brain is placed in a formal

ID: 52526 • Letter: 1

Question

1. ________ is the histological procedure in which a brain is placed in a formalin solution to halt autolysis and decomposition.

Fixation

Autoradiography

Perfusion

Staining


2. Which of the following is true of MRI scans?

MRI scans show greater spatial resolution than do CT scans.

MRI was the first method used to visualize the living human brain.

MRI scans can only view the horizontal plane.

MRI scans show less detail than do CT scans.

3. Which of the following techniques would be used to trace efferent axons from a brain region to other brain regions?

an anterograde labeling method

a retrograde labeling method

staining produced by cresyl violet

fluorogold


4. Dyes such as cresyl violet are useful for staining

cell bodies.

glial cells.

axons of passage.

dying neurons.


5. Which technique takes advantage of the requirement of glucose for more fuel?

2-DG autoradiography

electroencephalograph

microdialysis

c-FOS

6. Single-unit recordings

indicate that serotonergic neuron activity is silent during REM sleep.

represent summated neural activity of many neurons.

suggest that serotonin-containing neurons excite REM sleep.

are made using macroelectrodes placed on the skull surface.


7. The first technique used to visualize a living human brain was that of

computerized tomography.

microdialysis.

magnetic resonance imaging.

single-unit recording.


8. The key rationale for lesion studies is that

the change in behavior that follows a brain lesion can give important clues about a function of an ablated brain area.

lesions are simple to create within the brain.

brain lesions are specific for fibers of passage.

most lesions are temporary.

9. The key problem noted in Balint's syndrome is

difficulty in visual perception.

making errors in naming objects and colors.

difficulty in understanding the emotional content of speech.

difficulty breathing and chest pain.

10. The metabolic activity of a specific region of the living rat brain can be revealed by

measurement of Fos protein concentration.

MRI scans.

CT scans.

autoradiography of ghrelin concentration.


11. A ________ is an instrument used to slice the brain into thin pieces that can be preserved on a glass slide.

microtome

stereotaxic

mistotome

microscope

12. Imagine that feeding behavior was eliminated when a radio-frequency lesion was used to damage the lateral hypothalamus of a rat, which suggested that cells within this region initiate feeding. If a subsequent study failed to observe a change in feeding after injection of kainic acid into the lateral hypothalamus, what conclusion would be appropriate?

The changes in eating noted in the first study may be due to damage to axon fibers that are passing through the lateral hypothalamus.

The lateral hypothalamus functions to inhibit eating.

Glial cells within the lateral hypothalamus are key for the control of eating.

The changes in eating are due to damage to cell bodies within the lateral hypothalamus, and these act to initiate eating.

13. ___________ is a skull landmark which also serves as a reference point for stereotaxic surgery.

Bregma

Lambda

The optic chiasm

The junction of the parasagittal sutures

14. Stereotaxically guided lesions in humans have been used to treat

Parkinson's disease.

Alzheimer's disease.

Balint's syndrome.

angina pectoris.

Fixation

Autoradiography

Perfusion

Staining


Explanation / Answer

1. Fixation

2.MRI scans show greater spatial resolution than do CT scans.

3.an anterograde labeling method

4.axons of passage

5.2-DG autoradiography

6.represent summated neural activity of many neurons.

7.computerized tomography

8.the change in behavior that follows a brain lesion can give important clues about a function of an ablated brain area.

9.difficulty in visual perception

10.MRI scans.

11.microtome

12.Glial cells within the lateral hypothalamus are key for the control of eating.

13.Bregma

14.Parkinson's disease

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