Below are several statements about the structural features of nucleic acids. Som

Question

Below are several statements about the structural features of nucleic acids. Some are true only for DNA or RNA, some are true for both, and some do not fit either Which of the following statements is true for DNA only? O t contains the pyrimidine uracil. O t contains a 2 hydroxy group. O It contains the sugar 2-deoxyribose. O Bases are attached to sugars in an a N-glycosidic linkage. Which of the following statements is true for both DNA and RNA? O In base composition, %A -%C always. O Sugars are connected with a 3-5' phosphodiester link. O n base composition, %G -%C. O Both can be hydrolyzed in alkaline solution

Explanation / Answer

For DNA the following statement is true:

It contains the sugar 2'-deoxyribose.

DNA contains four bases namely adenine, guanine, cytosine and thymine. It does not contains an hydroxy group at 2'-position. In DNA the bases are connected with sugars through beta-N-glycosidic bond.

For both DNA and RNA the following statements are true:

Sugars are connected with 3'-5' phosphodiester link.

In base composition %G = %C.

In DNA the %G = %C and %A = %T and in RNA, %G = %C and %A = %U. Only RNA is hydrolysed in alkaline solution.

For RNA the following statement is true:

It commonly occurs in a variety of secondary structures.

Sugars in RNA are connected by 3'-5' phosphodiester bond. Both DNA and RNA contains purine adenine. RNA has single stranded helical structure.

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