BIOCHEM PROBLEM--During periods of intense activity, when glycolysis is used in

Question

BIOCHEM PROBLEM--During periods of intense activity, when glycolysis is used in the generation of ATP, the reaction lies to the right, decreasing [ADP], generating ATP, and accumulating AMP. However, [ATP] is usually much greater than [ADP], and [ADP] is greater than [AMP]. Determine [AMP] when 3% of the ATP in a hypothetical cell is hydrolyzed to ADP. In this cell, the initial concentration of ATP is 273 M, and the total adenine nucleotide concentration (the concentration of ATP, ADP, and AMP) is 366 M. The equilibrium constant K is 0.82 . What is the concentration of AMP after 3% of the ATP is hydrolyzed to ADP?

Explanation / Answer

Initial ATP concentration = 273uM

[ATP]+ [ADP]+[AMP] = 366uM

Keq= 0.82

The reaction is

ATP + AMP ------------> 2ADP

Keq= [ADP]2/ [ATP] [AMP] = 0.82

[ATP] + 1/2[ADP]/[ATP] + [ADP] + [AMP

Related Questions

Navigate

• Browse (All)
• Browse B
• Subjects

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.