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Hi, I need help on a biochem study question! Arrange the order of events in the

ID: 72985 • Letter: H

Question

Hi, I need help on a biochem study question!

Arrange the order of events in the fatty acid (FA) metabolism pathway in the correct order:

1) The modified FA is transported across the inner membrane of the mitochondrion.

2) Dehydration occurs to generate an ,-unsaturated FA.

3) The free FA is converted to acetyl CoA ester.

4) Thiolytic cleavage occurs, releasing a molecule of acetyl CoA and a new FA with two fewer carbon atoms.

5) The FA CoA ester is converted to its carnitine ester.

6) Hydration occurs to yield a -hydroxy ester.

7) The FA CoA ester is regenerated.

Explanation / Answer

Steps of fatty acid synthesis in an order are as follows:

3) The free FA is converted to acetyl CoA ester.

5) The FA CoA ester is converted to its carnitine ester.

1) The modified FA is transported across the inner membrane of the mitochondrion.

7) The FA CoA ester is regenerated.

2) Dehydration occurs to generate an ?, ?-unsaturated FA.

6) Hydration occurs to yield a ?-hydroxy ester.

4) Thiolytic cleavage occurs, releasing a molecule of acetyl CoA and a new FA with two fewer carbon atoms.

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