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What will be the expected effect of a mutation in the promoter region of an E. c

ID: 85433 • Letter: W

Question

What will be the expected effect of a mutation in the promoter region of an E. coli gene, at one of the consensus sites?

The rate of transcription could increase or decrease, depending on the particular mutation and the given promoter sequence.

The rate of transcription will likely decrease, because all promoters are optimized for high expression.

There will likely be no effect on transcription because other signals will still exist.

The rate of transcription will likely increase, because most promoters are not optimized for high expression.

The rate of transcription could increase or decrease, depending on the particular mutation and the given promoter sequence.

Explanation / Answer

option A.

RNA pol enzyme binds to the promoter site. it is a consensus sequence which means in different organism sequence may be different and because of that binding of RNA pol is also affected. if it is good because of the mutation, then we will get increase transcription and if poor binding because of mutation, we will get the decrease transcription or may be premature termination of transcription.

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