General Biochemistry Lecture I Assignment3 Problem 5 10 Problem 5.10 A geotein h
ID: 891600 • Letter: G
Question
General Biochemistry Lecture I Assignment3 Problem 5 10 Problem 5.10 A geotein has been sequenced after cleavage of disulfide bonds. The protein is known to conain 3 Cys residues, located as showm below. Only one of the Cys has a free-SH group and the other two are involved in an S-S bond The only mmethionine and the only aromatic amine acid (Phe) in this protein are in the ponitions indicaed Cleavage of the intact protein (ie with douflide bonds intact) by either cyanogen beomide or chymotrypsin does not break the protein into two pepides Part A Where is -S-8-bond(ie,AB. Be or AC? O BC O AC O AB DOLL P11 F6 9
Explanation / Answer
The correct option is AC.
Generally during the formation of S-S bond in proteins (or in amino acids), the 2 thiol groups one at adjacent to C-terminal and other at adjacent to N-terminal involes in S-S bond formation.
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