Enzyme X requires an allosteric activator in order to function properly. Which o
ID: 91424 • Letter: E
Question
Enzyme X requires an allosteric activator in order to function properly. Which of the following amino acids would be more likely to from electrostatic interactions with a negatively charged region of Enzyme X: a. MYA b. PFC c. RRH d. DQS e. EEE Glucose is at a higher concentration inside the cell while Na^+ is at a higher concentration outside the cell. Glucose needs to move inside the cell. How can glucose be transported inside the cell? a. Passive transport using a glucose transporter b. Active transport using a glucose transporter c. Coupled transport using Na^+ moving into the cell d. Active transport using a glucose-ATP pump e. Simple diffusion because glucose is unchargedExplanation / Answer
8.C.Only positively charged amino acids will form electrostatic interactions with negatively charged portion of enzyme X.Because there are only three positively charged amino acids present which are : lysine (Lys, K), arginine (Arg, R) and histidine (His, H) (basic side chains).Hence these will be the best option for electrostatic interactions.
Thus in the option RRH i.e 2 arginine and one histidine will form electrostatic interactions with the enzyme.
9.c. This is achieved through the action of the Na+/K+ pump, the energy for which is provided through the hydrolysis of ATP. Three Na+ ions are extruded from the cell in exchange for two K+ ions entering through the intramembrane enzyme Na+/K+-ATPase; this leaves a relative deficiency of Na+ in the intracellular compartment. Na+ ions diffuse down their concentration gradient into the columnar epithelia, co-transporting glucose. Once inside the epithelial cells, glucose reenters the bloodstream through facilitated diffusion through GLUT2 transporters.
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