In one large population both a G to A SNP and a 2.7kb deletion are associated wi
ID: 98864 • Letter: I
Question
In one large population both a G to A SNP and a 2.7kb deletion are associated with albinism. The frequency of the A allele of the SNP associated with albinism is 0.278 and the frequency of the presence of the deletion is 0.0128. The G allele and the absence of the deletion are associated with normal pigmentation. The population is assumed to be at Hardy-Weinberg equilibrium for each of these loci. Researchers suspect the loci are in linkage equilibrium. If the G to A SNP and the 2.7kb deletion are in linkage equilibrium then _____ minus _____ = ____. Which option best completes the prediction?
0.987 ; 0.0128 ; 0.974
0.713 ; 0.0036 ; 0.7094
0.722 ; 0.278 ; 0.444
0.00254 ; 0.00247; 0
0.998 ; 0.0025 ;1
a.0.987 ; 0.0128 ; 0.974
b.0.713 ; 0.0036 ; 0.7094
c.0.722 ; 0.278 ; 0.444
d.0.00254 ; 0.00247; 0
e.0.998 ; 0.0025 ;1
Explanation / Answer
Answer:
In one large population both a G to A SNP and a 2.7kb deletion are associated with albinism. The frequency of the A allele of the SNP associated with albinism is 0.278 and the frequency of the presence of the deletion is 0.0128. The G allele and the absence of the deletion are associated with normal pigmentation. The population is assumed to be at Hardy-Weinberg equilibrium for each of these loci. Researchers suspect the loci are in linkage equilibrium. If the G to A SNP and the 2.7kb deletion are in linkage equilibrium then 0.722 minus 0.278 = 0.444. Which option best completes the prediction?
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