Consider a population of 20 individuals. A certain locus is polymorphic in this

Question

Consider a population of 20 individuals. A certain locus is polymorphic in this population for two selectively neutral alleles (i.e. distinct, but do not affect fitness), with frequencies f(A1) = 0.70 and f(A2) = 0.30. Because the population is so small, random genetic drift will probably occur, with the resut that one of the two alleles will eventually be lost. What do you suppose is the probability that the A1 allele will be lost? That the A2 allele will be lost? How would this change if the population consisted of 2,000 individuals?

Explanation / Answer

f(A1) = 0.70

If we assume that the population is in H-W equilibrium, Then the frequency of this allele to tbe lost if, probability= square of the frequency of the allele.

From a population of 20 individual, 14 has chance of losing A1 and 6 has chance of losing A2.

P(loss of A1 in 2000 individual)= 0.007

P(loss of A2 in 2000 individual)= 0.003

F(A1) = 0.000049

F(A2)= 0.000009

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