Consider a population of Clostridium difficile living in the human gut. Regular
ID: 217613 • Letter: C
Question
Consider a population of Clostridium difficile living in the human gut. Regular ingestion of an antibiotic is a selective process on the gut ecosystem. Which of the following events could be considered adaptive mutations for C. difficile in this environment?
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Acquisition of a plasmid with a gene encoding an enzyme to inactivate the antibiotic
Deletion of the gene encoding a restriction endonuclease
Duplication of the gene encoding flagellin
Point mutation changing a single amino acid in a membrane transporter
Explanation / Answer
C. difficile infection or CDI is an infection caused by, Clostridium difficile. The symptoms include diarrhea, fever, nausea, and abdominal pain. CDI is spread by bacterial spores found in feces.
The following events could be considered adaptive mutations for C. difficile in this environment:
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