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Consider a population of Clostridium difficile living in the human gut. Regular

ID: 217613 • Letter: C

Question

Consider a population of Clostridium difficile living in the human gut. Regular ingestion of an antibiotic is a selective process on the gut ecosystem. Which of the following events could be considered adaptive mutations for C. difficile in this environment?

Check All That Apply

Acquisition of a plasmid with a gene encoding an enzyme to inactivate the antibiotic

Deletion of the gene encoding a restriction endonuclease

Duplication of the gene encoding flagellin

Point mutation changing a single amino acid in a membrane transporter

Explanation / Answer

C. difficile infection or CDI is an infection caused by, Clostridium difficile. The symptoms include diarrhea, fever, nausea, and abdominal pain. CDI is spread by bacterial spores found in feces.

The following events could be considered adaptive mutations for C. difficile in this environment:

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