8. Which among the listed effects is not produced by glucagon in the liver?: a.

Question

8. Which among the listed effects is not produced by glucagon in the liver?: a. inactivation of pyruvate kinase by cAMP-dependent kinase b. activation of protein kinase c. activation of glycogen synthetase d. activation of fructose 2,6-bisphosphatase e. inhibition of phosphofructokinase-2 9. von Gierke's disease is due to: defect in the -1 4 glucosidase b. glycogen phosphorylase c. phosphofructokinase-1 d. glycogen phosphorylase kinase 10. In which step glucagon completely blocks glycolysis? a. hexokinase reaction b. aldolase reaction c. phosphoglycerate kinase reaction d. phosphofructokinase 1 reaction e. enolase reaction 11. Which of the listed hormones is glcuconeogenic hormone? a. Insulin b. Glucocorticosteroid c. Thyroxin d. Growth hormone e. Melatonin 12. Which of the listed substances is allosteric inhibitor of the phosphofructokinase -1 ? 13. The liver responds to epinephrine by activating adenylyl cyclase through binding to 14. Release of Glucagon from the pancreas leads to a. NAD+ b. AMP c. CoA d. Citrate e. pyruvate A. GLUT4 B. a-receptor C. -receptor D, phospholipase C E. Ca2+ channel A. decreased gluconeogenesis in the liver B. increased glycogenogenesis in the liver C. no effect in the heart muscle D. stimulating glycolysis in the liver E. inhibition of glycolysis in the skeletal muscle 15. Which form of Glycogen synthase is active in synthesizing glycogen? A. m-glycogen synthase D. o-glycogen synthase C. none of the above B. phosphorylated glycogen synthase E. glycogen synthase b complexed with ATP 16. Phosphoprotein phosphatase-1 binds to glycogen in the liver and in the muscle. Name the enzyme that activates phosphoprotein phosphatase in muscle by phosphorylating GM protein: A. protein kinase A B. protein kinase C C. calmodulin-dependent protein kinase D. Insulin-dependent protein kinase 17. Which among listed molecules converts glycogen phosphorylase a from the R state to the Tstate: A. ATP B. Glucose C. G6P D. AMP E. GTP 18. Precursor for the glycogen synthesis is: A. Glucose-6-phosphate B. glucose C. Glucose-1-phosphate D. Fructose-1-phosphate E. Glucose-1,6-bisphosphat

Explanation / Answer

Question no 8) activation of glycogen synthetase.

Question no 9) glucose-6 phosphatase.

Question no 10) phosphofructoskinase-1 reaction.

Question no 11) insulin.

Question no 12)AMP.

Question no 13) B receptor

Question no 14) increased glycogenesis in liver.

Question no 15)

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